Olfactory Ensheathing Cells and CNS Regeneration
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چکیده
منابع مشابه
Olfactory Ensheathing Cells and CNS Regeneration The Sweet Smell of Success?
with OECs. These are the cells that ensheath the axons within the olfactory nerve and constitute the major glial component of the superficially located nerve fiber layer of the olfactory bulb. This property of the OEC to provide a permissive boundary between the PNS and CNS is The OEC, originally described by the Spanish histologist Blanes Viale at the end of the nineteenth century, shares prop...
متن کاملThe migration of olfactory ensheathing cells during development and regeneration.
The primary olfactory nervous system is unique in that it continuously renews itself and regenerates after injury. These properties are attributed to the presence of olfactory glia, termed olfactory ensheathing cells (OECs). Evidence is now emerging that individual OEC populations exist with distinct anatomical localisations and physiological properties, but their differential roles have not be...
متن کاملMeningeal cells enhance limited CNS remyelination by transplanted olfactory ensheathing cells.
Olfactory ensheathing cells (OECs) are candidate cells for transplant-mediated repair of persistent demyelination in diseases such as multiple sclerosis. If this approach is to make the transition from laboratory to clinic, an important issue is the most suitable composition of the OEC transplant. Isolation of OECs involves concurrent isolation of other cell types, and specific selection techni...
متن کاملOlfactory ensheathing cells and spinal cord repair.
The olfactory ensheathing cell is a specialized glial cell that assists in growth of the axons of the olfactory sensory neurons as they are generated and regenerated throughout adult life. There is increasing evidence in animal models that transplantation of olfactory ensheathing cell promotes recovery after transplantation into the injured spinal cord. Olfactory ensheathing cell transplants ha...
متن کاملCNPase Expression in Olfactory Ensheathing Cells
A large body of work supports the proposal that transplantation of olfactory ensheathing cells (OECs) into nerve or spinal cord injuries can promote axonal regeneration and remyelination. Yet, some investigators have questioned whether the transplanted OECs associate with axons and form peripheral myelin, or if they recruit endogenous Schwann cells that form myelin. Olfactory bulbs from transge...
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ژورنال
عنوان ژورنال: Neuron
سال: 2000
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)00080-5